Cartilage regeneration surgery in theatre

Cartilage regeneration compared

STACi vs OATS (Mosaicplasty): Two Ways to Rebuild Cartilage

OATS moves your own cartilage plugs; STACi grows new cartilage on a scaffold. Here is how to choose.

Quick answer

OATS (also called mosaicplasty) moves small plugs of your own cartilage and bone from a non-weight-bearing part of the joint into the damaged area. It works well for small-to-moderate defects but is limited by how much donor tissue can be spared and can cause donor-site symptoms. STACi grows new cartilage on a scaffold, with no donor plugs, for larger defects.

Both are genuine options at London Cartilage Clinic. OATS is well suited to small-to-moderate defects where healthy donor tissue can be spared; STACi is built for larger damage and takes no donor plugs.

OATS vs STACi at a glance

What to compareOATS / mosaicplastySTACi
What it doesMoves plugs of your own cartilage + bone from a non-weight-bearing area into the defectGrows your own cartilage cells on a 3D scaffold and places them into the defect
Tissue qualityReal, mature cartilage — but only as much as the donor area can spareHyaline-like cartilage regenerated in depth, no donor limit
Defect size it suitsSmall-to-moderate defectsLarger and more complex defects
Donor tissue harvestedYes — cartilage/bone plugs from the same jointNo donor plugs
Donor-site morbidityPossible — pain or problems where the plugs were takenNone — nothing healthy is removed
OperationsOneOne in most cases
JointsMainly knee (also ankle)Any joint
Available at LCCYes — from £14,000Yes — from £28,000, all-inclusive

Both procedures are offered at LCC; this is a genuine choice, not a takedown of OATS.

When OATS may be the better choice

  • Your defect is small-to-moderate and there is enough healthy, non-weight-bearing cartilage to spare as donor plugs.
  • You want an established single-operation technique using mature cartilage straight away, rather than regenerated tissue.
  • Your surgeon judges the location and size are well matched to what donor plugs can resurface.
  • Cost is a consideration — OATS at LCC is from £14,000.

When STACi is the better choice

  • Your defect is larger or more complex than the available donor supply can resurface.
  • You would rather not take healthy cartilage and bone from elsewhere in the joint, avoiding any donor-site problems.
  • The damage spans an area where placing multiple plugs would be difficult.
  • You want scaffold-based regeneration that can build cartilage in depth as well as across the surface.

OATS is a proven, effective operation and a real option here — for the right small-to-moderate defect, moving a patient’s own mature cartilage can give an excellent result in a single sitting. Its two natural limits are supply (the same joint can only spare so much healthy tissue) and the donor site itself (taking plugs can occasionally cause symptoms where they came from). STACi removes both limits — nothing healthy is harvested, and defect size is not capped by donor supply — at a higher price and with regenerated rather than pre-formed cartilage. Because we offer both, the consultation is a genuine “which suits your joint”, not a sales pitch for one.

Cartilage cells on a scaffold prepared at London Cartilage Clinic
STACi grows new cartilage on a scaffold, with no donor plugs taken from elsewhere in the joint.
consulting-in-office-with-pen

Frequently Asked Questions

What is the difference between OATS and STACi?

OATS (mosaicplasty) takes small plugs of your own cartilage and bone from a non-weight-bearing part of the joint and transfers them into the damaged area — mature cartilage, moved in one operation. STACi instead grows your own cartilage cells on a 3D scaffold and places that into the defect. OATS is limited by donor supply and suits small-to-moderate defects; STACi takes no donor plugs and is built for larger damage.

Does London Cartilage Clinic offer OATS as well as STACi?

Yes. OATS is a genuine option at LCC, from £14,000, and STACi is from £28,000, all-inclusive. Which one suits you depends on the size, depth and location of your cartilage damage and how much healthy donor tissue can be spared. The consultation exists to make that choice honestly, not to push one procedure.

What is donor-site morbidity, and does STACi avoid it?

Donor-site morbidity means pain or problems at the place healthy tissue was taken from. Because OATS harvests cartilage-and-bone plugs from elsewhere in the joint, that donor area can occasionally become symptomatic. STACi takes no donor plugs — nothing healthy is removed — so there is no donor site to cause problems. That is one reason STACi can suit larger defects, where OATS would need to borrow more tissue.

Is OATS or STACi better for a larger cartilage defect?

Larger defects tend to favour STACi. OATS is capped by how much donor cartilage the same joint can spare, so bigger areas can be hard to resurface with plugs. STACi’s scaffold-based regeneration is not limited by donor supply and is designed for larger, more complex damage. For a small-to-moderate defect, OATS remains a strong option. An imaging review settles it.

How long is recovery after STACi compared with OATS?

For STACi, recovery is staged: protected weight-bearing on crutches for six to eight weeks, early range-of-motion with physiotherapy, low-impact activity from four to six months, and higher-impact sport from nine to twelve months depending on the defect. OATS rehabilitation follows a broadly similar protected pathway. See the STACi recovery timeline for the detail.

Still have more specific concerns?

Free Discovery Call

OATS or STACi — let us look at your scan.

Because we offer both, the fairest next step is a review of your imaging. Start with a free discovery call, or book a consultation with the surgeon who would perform either procedure.

London Cartilage Clinic

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